Cleavage Enzyme definition

Cleavage Enzyme means any enzyme that (A) recognizes the structure formed by the hybridization of an Invader Probe and a Primary Probe to their cognate Target sequence such that the Invader Probe overlaps, at its 3' terminus by at least one nucleotide, the duplex formed by the hybridization of the Primary Probe to the complementary region of the Target; (B) cleaves the Non-Hybridizing Region from the Primary Probe when such structure exists; and (C) has limited or no nucleic acid synthesis ability. It is acknowledged and agreed that Cleavage Enzymes shall include enzymes having the three properties described in (A), (B), and (C) of this Section 1.6 above, regardless of whether or not the enzyme has other properties or uses, including causing cleavage under different circumstances, or cleaves additional nucleic acid bases along with the Non-Hybridizing Region. Cleavage Enzyme shall include those enzymes identified on Exhibit 2.2 in the Supply Agreement.
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Cleavage Enzyme. Cleavase Enzyme," "Confidential Information," "Development and Commercialization Agreement," "Diagnostic Procedures," "Enabled Customer," "End User," "GAAP," "Gene Expression Field," "Genotyping Field," "Intellectual Property Rights," "InvaderCreator Access Agreement," "Invader Reaction," "Licensed Product," "Multiplexed Invader Application," "Patents," "Probe Set," and "Target," shall have the meaning given to the particular term in the License Agreement.
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Cleavage Enzyme. Development and Commercialization Agreement," "Enabled Customer," "Gene Expression Field," "Genotyping Field," "Intellectual Property Rights," "Invader Probe," "Licensed Product," "Manufacturing Distributor," "Party," "Parties," "Patent," "Primary Probe," "Target," "Technology," "Technology Access Partner," "Third Party" and "Value Added Distributor" shall have the meaning given to the particular term in the License Agreement. Invader(R) and Cleavase(R) are registered trademarks of TWTI, but are printed in this Agreement without the registration ▇▇▇▇ for convenience. Similarly, InvaderCreator is a trademark of TWTI, but is printed in this Agreement without the TM ▇▇▇▇ for convenience. Confidential treatment has been requested for portions of this exhibit. The copy filed herewith omits the information subject to the confidentiality request. Omissions are designated as * * *. A complete version of this exhibit has been filed separately with the Securities and Exchange Commission.
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Examples of Cleavage Enzyme in a sentence

  • The Parties shall use commercially reasonable efforts to complete such development within sixty (60) days of the Effective Date, and to incorporate such eTag Functional Assay into the Specifications for the applicable Cleavage Enzyme and Standard Operating Procedures therefor promptly thereafter.

  • If, within a period of thirty (30) days after TWTI's receipt from ACLA of a Statement of Non-Compliance, TWTI is unable to verify that the applicable Cleavage Enzyme failed to conform to the Specifications at the time of original delivery by TWTI to the carrier, then the matter shall be submitted to and be finally decided by a nationally recognized independent testing laboratory if requested by either Party.

  • It is acknowledged and agreed that TWTI may segregate the Deposit Materials under separate escrow agreements for each Cleavage Enzyme so that only those Deposit Materials pertaining to the manufacture of the particular Cleavage Enzyme for which a Release Condition has occurred will be released to ACLA.

  • TWTI shall bear any out-of-pocket costs and expenses incurred by ACLA as required to implement the recall, or replacement, of any Cleavage Enzyme from Affected Lots.

  • Subject to Section 2.5(c) below, TWTI shall have the right to increase the Transfer Price for each Cleavage Enzyme under this Agreement in each calendar year by an amount that does not exceed the total aggregate percentage increase in the CPI Index for the preceding calendar year.

  • All Cleavage Enzyme obtained by ACLA under this Agreement shall be labeled, prior to distribution by ACLA to any other party, with the TWTI Marks in accordance with Section 3.7 of the License Agreement and with the field of use restrictions applicable in accordance with this Agreement and the License Agreement.

  • Likewise, if the Specifications include a functional requirement requiring in accordance with Standard Operating Procedures an eTag Functional Assay (as defined in Section 2.4(e) above), then ACLA shall provide, at no charge to TWTI, such software and reasonable quantities of such reagents reasonably sufficient for TWTI to perform such eTag Assay to analyze Cleavage Enzyme for shipment to ACLA for conformance with Specifications hereunder.

  • All of ACLA's orders for Cleavage Enzyme shall be made pursuant to such written purchase order form and shall provide for shipment in compliance with Section 2.6. TWTI shall use reasonable _______________ *** Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission.

  • For clarity, it is understood and agreed that title to all Cleavage Enzyme supplied by or on behalf of TWTI hereunder shall transfer to ACLA upon acceptance thereof by ACLA in accordance with Section 2.8(a) below, however risk of loss of Cleavage Enzyme shall transfer to ACLA at the time of delivery to the carrier for transport to ACLA's designated point of delivery.

  • Within thirty (30) days of receiving a shipment of Cleavage Enzyme and accompanying Quality Assurance Certificate, ACLA shall inform TWTI pursuant to Section 2.9, that said shipment either conforms to Specifications by delivering to TWTI an Acceptance Certificate or does not conform to such Specifications by delivering to TWTI a Statement of Non-Compliance.


More Definitions of Cleavage Enzyme

Cleavage Enzyme means any enzyme that (A) recognizes the structure formed by the hybridization of an Invader Probe and a Primary Probe to their cognate Target sequence such that the Invader Probe overlaps, at its 3' terminus by at least one nucleotide, the duplex formed by the hybridization of the Primary Probe to the complementary region of the Target; (B) cleaves the Non-Hybridizing Region from the Primary Probe when such structure exists; and (C) has limited or no nucleic acid synthesis ability. It is acknowledged and agreed that Cleavage Enzymes shall include enzymes having the three properties described in (A), (B), and (C) of this Section 1.6 above, regardless of whether or not the enzyme has other properties or uses, ____________________ *** Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions. including causing cleavage under different circumstances, or cleaves additional nucleic acid bases along with the Non-Hybridizing Region. Cleavage Enzyme shall include those enzymes identified on Exhibit 2.2 in the Supply Agreement.
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