Checkmate definition
Examples of Checkmate in a sentence
In Checkmate 025, serious adverse reactions occurred in 47% of patients receiving OPDIVO (n=406).
In Checkmate 017 and 057, serious adverse reactions occurred in 46% of patients receiving OPDIVO (n=418).
In Checkmate 066, serious adverse reactions occurred in 36% of patients receiving OPDIVO (n=206).
In Checkmate 067, serious adverse reactions (73% and 37%), adverse reactions leading to permanent discontinuation (43% and 14%) or to dosing delays (55% and 28%), and Grade 3 or 4 adverse reactions (72% and 44%) all occurred more frequently in the OPDIVO plus YERVOY arm (n=313) relative to the OPDIVO arm (n=313).
In Checkmate 275, the most common adverse reactions (≥ 20%) reported in patients receiving OPDIVO (n=270) were fatigue (46%), musculoskeletal pain (30%), nausea (22%), and decreased appetite (22%).
In Checkmate 275, serious adverse reactions occurred in 54% of patients receiving OPDIVO (n=270).
In Checkmate 205 and 039, adverse reactions leading to discontinuation occurred in 7% and dose delays due to adverse reactions occurred in 34% of patients (n=266).
In Checkmate 037, the most common adverse reaction (≥20%) reported with OPDIVO (n=268) was rash (21%).
In Checkmate 040, immune-mediated hepatitis requiring systemic corticosteroids occurred in 5% (8/154) of patients receiving OPDIVO.
In Checkmate 037, serious adverse reactions occurred in 41% of patients receiving OPDIVO (n=268).