CD3 definition

CD3 means the complex comprising the epsilon, delta and gamma subunits of the CD3 receptor complex (including any subtypes, alleles, and splice variants).
CD3 means the human cluster of differentiation 3 multimeric protein complex comprised in whole or in part of CD3 epsilon/delta, CD3 epsilon/gamma, and CD3 zeta/zeta dimers.
CD3 means cluster of differentiation 3.

Examples of CD3 in a sentence

  • The Lead Servicer, each Non-Lead Master Servicer and any Trustee will be entitled to interest on any Advance made in the manner and from the sources provided in the CD3 PSA or the Note A-2 PSA, as applicable.

  • The originals of all of the Mortgage Loan Documents (other than Note A-2) will be held by the CD3 Trustee (or by a custodian on its behalf) under the terms of the CD3 PSA on behalf of all of the Holders.

  • Except for the Initial Lifetime Asset Management Plan, any Fixed Asset Management Costs for any Asset Management Work to be carried out in any Planning Period N and included in the applicable LAMP will be at the level of at least a Class 2 estimate and at Stage Gate CD3 in accordance with the BP Project Management Guidelines, as determined by the Generator acting in good faith.

  • CD4+ T cell stimulation Naive CD4+ T cells were either left unstimulated or stimulated by cross-linking the CD3 receptor (simulating TCR ligation), with flagellin (to activate TLR5), with both stimuli (TCR + TLR5 activation), or by cross-linking CD3 and CD28 (TCR + CD28 activation).

  • To evaluate the purity of cell preparations, the following markers were evaluated by extracellular staining: CD3, CD4, CD45RO, CD45RA, CCR7, and CD62L.

  • BLINCYTO® (blinatumomab) is the first bispecific CD19-directed CD3 T cell engager (BiTE®) antibody construct product, and the first single-agent immunotherapy to be approved by the U.S. Food and Drug Administration (FDA) for the treatment of patients with Philadelphia chromosome-negative (Ph-) relapsed or refractory B-cell precursor ALL, a rare and rapidly progressing cancer of the blood and bone marrow.

  • T-cell stimulation could be induced using solid phase ephrin B2 and sub-optimal amounts of CD3.

  • Those that express CD3 will be cultured with anti-CD3 to crosslink the TCR and test for the upregulation of CD25 and production of IL-2 (Appendix A).

  • For clarity, such license does not include any right to manufacture, sell, supply, use or import any products which contain GNE’s CD3 Effector (including anti-CD3 antibodies, antigen-binding fragments thereof and other derivatives and variants).

  • The most widely-known murine HSC population is the LSK population, standing for lack of lineage markers (B220, Mac-1, Gr-1, CD3, CD4, CD8, and Ter119), and the presence of Sca1 and c-Kit.


More Definitions of CD3

CD3 means [***]
CD3 means the CD3 T-cell co-receptor, including the ▇▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇, ▇▇▇▇▇▇▇▇▇▇, and CD3zeta chains.

Related to CD3

  • Antibody means a molecule or a gene encoding such a molecule comprising or containing one or more immunoglobulin variable domains or parts of such domains or any existing or future fragments, variants, modifications or derivatives thereof.