ADME definition
Examples of ADME in a sentence
A dismissal decision must involve the CCC, the program director, the departmental chair (if applicable), the assistant DIO/site ADME, and UCF GME and HR.
As soon as reasonably practicable following the Effective Date, Curis will disclose to Genentech for use in connection with the Collaboration all chemical structures, pre-clinical data and reports (e.g., PK, ADME, toxicology, etc.) on the Compounds, to the extent in the possession and Control of Curis.
These studies at BI include confirmation of activity in human adipocytes and initial absorption, distribution, metabolism and excretion (ADME) characterization.
MT-3724 is administered as an infusion and has predictable PK and ADME characteristics.
The program director will use the template remediation letter found on MedHub, with review by site ADME, and fully signed copies uploaded to the resident's folder on MedHub.
The notice of non-renewal of contract must use a templated format and be approved by the assistant DIO/site ADME and UCF GME and HR, with signed copy forwarded to GME office.
If deficiencies in professional competence that may endanger patients arise during continued training under a non-renewal status, the trainee may be terminated or suspended immediately after consultation with the assistant DIO/site ADME and UCF HR.
A key ADME assay is to determine the stability of a compound in the presence of human liver microsomes.
In addition, the Hospital Chief Medical Officer, a hospital site director or core faculty member may also place a trainee on administrative leave for an event occurring at that site; however the program director, the site ADME, UCF HR and UCF GME office must be notified immediately.
From the perspective of in vitro ADME, we will be designing and selecting lead structures with acceptable plasma protein binding and metabolic profiles to attain acceptable human in vivo bioavailability, and lack of CYP interactions to obviate any potential drug/drug interactions.