0001753926-25-000276 Sample Contracts

SECOND AMENDMENT TO PLACEMENT AGENT AGREEMENT
Placement Agent Agreement • February 24th, 2025 • Lipella Pharmaceuticals Inc. • Pharmaceutical preparations • New York

This Second Amendment to Placement Agent Agreement (the “Amendment”) is made as of February 23, 2025, by and between Lipella Pharmaceuticals Inc. (the “Company”) and Spartan Capital Securities, LLC (the “Placement Agent”). Capitalized terms used but not defined herein shall have the meanings ascribed to them in the Placement Agent Agreement (defined below), as applicable.