0001628280-23-008187 Sample Contracts

THIRD AMENDMENT TO THE MANUFACTURING AND SERVICES AGREEMENT
Manufacturing and Services Agreement • March 16th, 2023 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations

This Third Amendment to the Manufacturing and Services Agreement (the “Third Amendment”) is made as of October 15, 2022 (the “Effective Date”) by and between Paratek Pharmaceuticals, Inc., a Delaware corporation with a principal business address at 75 Park Plaza, 4th Floor, Boston, MA 02116, United States (“Paratek”) and Almac Pharma Services Limited, a company organized and existing under the laws of Northern Ireland with an address at Almac House, 20 Seagoe Industrial Estate, Craigavon, BT63 5QD, Northern Ireland (“Almac”) and together with Paratek, the “Parties”. Capitalized terms used, but not otherwise defined, herein shall have the meanings set forth in the Agreement.

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Confirmation of Lease • March 16th, 2023 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations

This First Amendment to Lease (“Amendment”) made and entered into this 30 day of April, 2015, by and between ATLANTIC AMERICAN PROPERTIES TRUST, a Maryland real estate investment trust (“Landlord”) and PARATEK PHARMA, LLC, a Delaware limited liability company (mistakenly referred to as “Paratek Pharmaceuticals, LLC” in the Original Lease) (“Tenant”).

TREATS AS PRIVATE OR CONFIDENTIAL. SIXTH AMENDMENT TO THE AMENDED AND RESTATED MANUFACTURING AND SERVICES AGREEMENT
Manufacturing and Services Agreement • March 16th, 2023 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations

This Sixth Amendment to the Amended and Restated Manufacturing and Services Agreement (the “Sixth Amendment”) is made as of 2/23/2023 (the “Sixth Amendment Effective Date”) by and between Paratek Pharmaceuticals, Inc., a Delaware corporation with a principal business address at 1000 First Avenue, Suite 200, King of Prussia, PA 19406 (“Paratek”) and CIPAN ̵̶ Companhia Industrial Produtora de Antibióticos, S.A., a corporation organized and existing under the laws of Portugal with an address at Rua da Estação, no42, 2600-726 Castanheira do Ribatejo, Portugal (“CIPAN” and together with Paratek, the “Parties”). Capitalized terms used, but not otherwise defined, herein shall have the meanings set forth in the Agreement.

Contract
Product Agreement • March 16th, 2023 • Paratek Pharmaceuticals, Inc. • Pharmaceutical preparations

CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED WITH [***], HAS BEEN OMITTED BECAUSE IT IS BOTH (I) NOT MATERIAL AND (II) IS THE TYPE THAT THE REGISTRANT TREATS AS PRIVATE OR CONFIDENTIAL.

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