0001609351-16-000015 Sample Contracts

FIRST AMENDMENT TO SUBLEASE AGREEMENT
Sublease Agreement • February 5th, 2016 • Spark Therapeutics, Inc. • Biological products, (no disgnostic substances)

THIS FIRST AMENDMENT TO SUBLEASE AGREEMENT (the “Amendment”) by and between PRESBYTERIAN MEDICAL CENTER OF THE UNIVERSITY OF PENNSYLVANIA HEALTH SYSTEM d/b/a PENN PRESBYTERIAN MEDICAL CENTER, (the “Sublessor”), and SPARKS THERAPEUTICS, INC. (the “Sublessee”) dated November 10, 2015, (the Sublease) is entered into by the Parties on this 1st day of February, 2016, and shall be effective in accordance with the provisions of Paragraph 5 below.

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