0001564590-22-009097 Sample Contracts

FOURTH AMENDMENT TO LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • March 8th, 2022 • Durect Corp • Pharmaceutical preparations

THIS FOURTH AMENDMENT to Loan and Security Agreement (this “Amendment”) is entered into as of March 3, 2021 (the “Amendment Date”), by and among OXFORD FINANCE LLC, a Delaware limited liability company with an office located at 115 South Union Street, Suite 300, Alexandria, Virginia 22314 (“Oxford”), as collateral agent (in such capacity, “Collateral Agent”), the Lenders listed on Schedule 1.1 to the Loan Agreement (as defined below) or otherwise a party thereto from time to time including Oxford in its capacity as a Lender (each a “Lender” and collectively, the “Lenders”), and DURECT CORPORATION, a Delaware corporation with offices located at 10260 Bubb Road, Cupertino, California 95014 ( “Borrower”).

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LICENSE AGREEMENT by and between DURECT CORPORATION and INNOCOLL PHARMACEUTICALS LIMITED dated December 21, 2021
License Agreement • March 8th, 2022 • Durect Corp • Pharmaceutical preparations • Delaware

This LICENSE AGREEMENT (the “Agreement”) is effective as of December 21, 2021 (the “Effective Date”) by and between Innocoll Pharmaceuticals Limited, a company incorporated in Ireland having company number 395965 and having its registered office at 70 Sir John Rogerson’s Quay, Dublin 2, D02 R296, Ireland (“INNOCOLL”), and Durect Corporation, a Delaware corporation having a place of business at 10260 Bubb Road, Cupertino, California 95014 (“DURECT”). INNOCOLL and DURECT may each be referred to herein by name or, individually, as a “Party” and, collectively, as the “Parties.”

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