0001564590-21-042229 Sample Contracts

SECOND SUPPLEMENTAL INDENTURE
Second Supplemental Indenture • August 9th, 2021 • Syneos Health, Inc. • Services-commercial physical & biological research • New York

Second Supplemental Indenture (this “Supplemental Indenture”), dated as of May 25, 2021, among each undersigned Subsidiary (the “Guaranteeing Subsidiaries”), each a subsidiary of Syneos Health, Inc. (or its permitted successor), a Delaware corporation (the “Company”), the Company, the other Guarantors (as defined in the Indenture referred to herein) and Wells Fargo Bank, National Association, as trustee under the Indenture referred to below (the “Trustee”).

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SYNEOS HEALTH, INC. 2018 Equity Incentive Plan Global Restricted Stock Unit Award Agreement for Directors
Global Restricted Stock Unit Award Agreement for Directors • August 9th, 2021 • Syneos Health, Inc. • Services-commercial physical & biological research • Delaware

This Global Restricted Stock Unit Award Agreement for Directors (the “Agreement”) is made by and between Syneos Health, Inc., a Delaware corporation (the “Company”), and [INSERT NAME] (the “Participant”), effective as of [INSERT DATE OF GRANT] (the “Date of Grant”).

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