0001564590-18-021046 Sample Contracts

Amendment No.1 to the License Agreement
License Agreement • August 9th, 2018 • Puma Biotechnology, Inc. • Pharmaceutical preparations

PUMA Biotechnology, Inc., a company incorporated in Delaware, United States of America, with its principal place of business at 10880 Wilshire Blvd., Suite 2150, Los Angeles, CA 90024 ("PUMA");

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FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • August 9th, 2018 • Puma Biotechnology, Inc. • Pharmaceutical preparations • California

THIS FIRST AMENDMENT to Loan and Security Agreement (this “Amendment”) is entered into as of May 8, 2018, among SILICON VALLEY BANK, a California corporation with an office located at 3003 Tasman Drive, Santa Clara, CA 95054 (“Bank” or “SVB”), as administrative and collateral agent (in such capacities, “Administrative Agent” and “Collateral Agent”, respectively), the Lenders listed on Schedule 1.1 of the Loan Agreement (as defined below) or otherwise party thereto from time to time (each a “Lender” and collectively, the “Lenders”) including SVB in its capacity as a Lender and OXFORD FINANCE LLC, a Delaware limited liability company with an office located at 133 North Fairfax Street, Alexandria, Virginia 22314 (“Oxford”) (each a “Lender” and collectively, the “Lenders”), and PUMA BIOTECHNOLOGY, INC., a Delaware corporation with offices located at 10880 Wilshire Blvd., Ste. 2150, Los Angeles, CA 90024 (“Borrower”).

SUPPLY AGREEMENT BETWEEN PUMA BIOTECHNOLOGY, INC AND SPECIALISED THERAPEUTICS ASIA PTE LTD (Singapore)
Supply Agreement • August 9th, 2018 • Puma Biotechnology, Inc. • Pharmaceutical preparations • New York

This supply agreement (“Supply Agreement”) is made as of 20 April 2018 (“Effective Date”), by and between PUMA Biotechnology, Inc., a company incorporated in Delaware, United States of America, with its principal place of business at 10880 Wilshire Blvd., Suite 2150, Los Angeles, CA 90024 (“PUMA”), as licensor, and Specialised Therapeutics Asia Pte Ltd., a proprietary limited company incorporated under the laws of the Republic of Singapore, with its principal place of business at 50 Raffles Place, #32-01, Singapore Land Tower, Singapore, 048623 (“STA”), as licensee. PUMA and STA are sometimes referred to herein individually as a “Party” and collectively as the “Parties”.

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