0001564590-18-018845 Sample Contracts

FIRST AMENDMENT TO THE DEVELOPMENT AND COMMERCIALIZATION AGREEMENT
Development and Commercialization Agreement • August 2nd, 2018 • Durect Corp • Pharmaceutical preparations

This FIRST AMENDMENT TO THE DEVELOPMENT AND COMMERCIALIZATION AGREEMENT, dated May 5, 2017 (the “First Amendment”) is effective as of May 4, 2018 (the “Amendment Effective Date”) by and between Sandoz AG, a company organized under the laws of Switzerland, with an office at Lichtstraβe 35, CH 4056, Basel, Switzerland (“SANDOZ”), and Durect Corporation, a Delaware corporation having a place of business at 10260 Bubb Road, Cupertino, California 95014 (“DURECT”). SANDOZ and DURECT are each referred to herein by name or, individually, as a “Party” or, collectively, as the “Parties.”

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ADDENDUM III TO
Durect Corp • August 2nd, 2018 • Pharmaceutical preparations • Delaware

This Addendum III to the Lease is attached to, made part of, and incorporated into that certain Lease dated April 23, 2008 by and between NORTHWEST ASSET MANAGEMENT, as authorized agent for Branagh Family 2000 Trust, Patterson Family Trust et al as Tenants in Common ("Lessor"), and DURECT Corporation, a Delaware corporation ("Lessee"), with reference to the certain real Property known as 830 Eubanks Drive, Suites A, B & C, City of Vacaville, County of Solano, State of California ("Premises").

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