0001564590-18-004560 Sample Contracts

ADVERUM BIOTECHNOLOGIES, INC. CHANGE IN CONTROL AND SEVERANCE AGREEMENT
Change in Control and Severance Agreement • March 6th, 2018 • Adverum Biotechnologies, Inc. • Biological products, (no disgnostic substances) • California

This Change in Control and Severance Agreement (the “Agreement”) is made and entered into by and between ________________ (“Executive”) and Adverum Biotechnologies, Inc. (the “Company”), effective as of the latest date set forth by the signatures of the parties hereto below (the “Effective Date”).

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RELEASE AGREEMENT
Release Agreement • March 6th, 2018 • Adverum Biotechnologies, Inc. • Biological products, (no disgnostic substances) • California

This Release Agreement (this “Agreement”) is entered into as of October 3, 2017 between Steven Schwartz, M.D. (“Director”) and Adverum Biotechnologies, Inc. (the “Company”).

AMENDMENT TO COLLABORATION, OPTION AND LICENSE AGREEMENT
Collaboration, Option and License Agreement • March 6th, 2018 • Adverum Biotechnologies, Inc. • Biological products, (no disgnostic substances) • Delaware

This Amendment (“Amendment”) is entered into as of January 25, 2018 (the “Amendment Effective Date”), by and between Adverum Biotechnologies, Inc., a Delaware corporation having an address at 1035 O’Brien Drive, Menlo Park, CA 94025 (“Adverum”), and Editas Medicine, Inc., a Delaware corporation having an address at 11 Hurley St., Cambridge, MA 02141 (“Editas”) and amends that certain Collaboration, Option and License Agreement, dated August 8, 2016, by and between Adverum and Editas (the “Agreement”). Adverum and Editas may be referred to herein individually as a “Party” and collectively as the “Parties.”

Re: Employment Terms for Sr. Patent Counsel/Director IP
Letter Agreement • March 6th, 2018 • Adverum Biotechnologies, Inc. • Biological products, (no disgnostic substances)

This letter agreement (the "Agreement") memorializes the employment terms for your anticipated hire by Avalanche Biotechnologies, Inc. (the "Company") in the position of Sr. Patent Counsel/ Director IP reporting to Hans Hull, SVP Business Operations. These terms will become effective on June 2, 2015 or at such later date by mutual agreement and as approved by the Board of Directors of the Company (as applicable, the "Hire Date").

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