0001559053-19-000035 Sample Contracts

CONSULTING AGREEMENT
Consulting Agreement • November 5th, 2019 • Prothena Corp PLC • Pharmaceutical preparations • California

This Consulting Agreement (this “Agreement”) is effective as of July 1, 2019 (the “Effective Date”) and is made by and between Dennis J. Selkoe, M.D., an individual (“Consultant”), and Prothena Biosciences Inc, a Delaware corporation with offices at 331 Oyster Point Boulevard, South San Francisco, CA 94080, U.S.A. (“Prothena”). Consultant and Prothena may each be referred to individually herein as a “Party” and collectively as the “Parties”.

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July 1, 2019 Bill Homan Re: Amended and Restated Retirement Transition Letter Agreement Bill,
Prothena Corp PLC • November 5th, 2019 • Pharmaceutical preparations

This letter confirms the following in connection with your decision to retire from Prothena Biosciences Inc (the “Company”), and amends and restates in its entirety the Retirement Transition Letter Agreement dated December 11, 2018 between you and the Company (the “Existing Agreement”):

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