0001558370-25-002867 Sample Contracts

Certain information marked as [***] has been excluded from this exhibit because it is both not material and is the type that the registrant treats as private or confidential.
Framework Agreement • March 13th, 2025 • MeiraGTx Holdings PLC • Biological products, (no disgnostic substances) • England and Wales

This Framework Agreement (as may be amended from time to time, this “Agreement”), dated as of March 9, 2025 (the “Effective Date”), is made as a DEED by and among:

COLLABORATION, OPTION AND LICENSE AGREEMENT BY AND BETWEEN Janssen Pharmaceuticals, Inc., MEIRAGTX UK II LIMITED AND MEIRAGTX HOLDINGS PLC
Collaboration, Option and License Agreement • March 13th, 2025 • MeiraGTx Holdings PLC • Biological products, (no disgnostic substances) • New York

This Collaboration, Option and License Agreement (this “Agreement”) is made as of January 30, 2019 (the “Execution Date”), by and between Janssen Pharmaceuticals, Inc., a Pennsylvania corporation located at 1125 Trenton-Harbourton Road, Titusville, NJ 08560, United States of America (“Janssen”), on the one hand, and MeiraGTx UK II Limited, a company organized and existing under the laws of England, located at 25 Provost Street, London N1 7NH, United Kingdom and MeiraGTx Holdings plc, a Cayman Islands corporation located at 430 East 29th Street, 10th Floor, New York, NY 10016, United States of America (MeiraGTx UK II Limited and MeiraGTx Holdings plc, individually or collectively, “MeiraGTx”), on the other hand. Janssen and MeiraGTx are each referred to individually as a “Party” and together as the “Parties.”

Certain information marked as [***] has been excluded from this exhibit because it is both not material and is the type that the registrant treats as private or confidential. FORM OF COLLABORATION AND LICENSE AGREEMENT by and among HOLOGEN NEURO AI...
Collaboration and License Agreement • March 13th, 2025 • MeiraGTx Holdings PLC • Biological products, (no disgnostic substances) • New York

THIS COLLABORATION AND LICENSE AGREEMENT (this “Agreement”) dated as of ____, 2025 (the “Effective Date”), is entered into by and among (a) (i) HOLOGEN NEURO AI UK LIMITED, a private company limited by shares incorporated in England with company number 16283812 and having a place of business at 86-87 Campden Street, London W8 7EN, UK (“Hologen UK”), and (ii) HOLOGEN NEURO AI LTD, a non-cellular company limited by shares incorporated in Guernsey with company number 74942 whose registered office is at c/o Elysium Fund Management, 1st Floor, Royal Chambers, St Julian’s Avenue, St Peter Port, GY1 3JX, Guernsey (“Hologen Guernsey” and, together with Hologen UK, “Company”); (b) HOLOGEN LIMITED, a non-cellular company limited by shares incorporated in Guernsey with company number 74905 whose registered office is at c/o Elysium Fund Management, 1st Floor, Royal Chambers, St. Julian’s Avenue, St. Peter Port, GY1 3JX, Guernsey (“HGL”); and (c) (i) MEIRAGTX NEURO I, LLC, a Delaware limited liabil