0001558370-18-001865 Sample Contracts

AMENDED AND RESTATED EMPLOYMENT AGREEMENT
Employment Agreement • March 12th, 2018 • Strongbridge Biopharma PLC • Pharmaceutical preparations • Pennsylvania

THIS AMENDED AND RESTATED EMPLOYMENT AGREEMENT (the “Agreement”) is made by and between Strongbridge U.S. Inc., a Delaware corporation (the “Company”), and ___________________ (“Executive”) as of October 13, 2017.

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RESTRICTED STOCK UNIT AWARD
Restricted Stock Unit Award Agreement • March 12th, 2018 • Strongbridge Biopharma PLC • Pharmaceutical preparations • Delaware

This RESTRICTED STOCK UNIT AWARD AGREEMENT (the “Agreement”), dated as of [DATE], (the “Date of Grant”) is delivered by Strongbridge Biopharma plc (the “Company”), to [NAME] (the “Grantee”).

LICENSE AND ASSIGNMENT AGREEMENT
License and Assignment Agreement • March 12th, 2018 • Strongbridge Biopharma PLC • Pharmaceutical preparations • New York
FORM OF WARRANT
Strongbridge Biopharma PLC • March 12th, 2018 • Pharmaceutical preparations • New York

THIS CERTIFIES THAT, for value received, [__], or its registered assigns (the “Holder”), is entitled, subject to the provisions and upon the terms and conditions set forth herein, to purchase from STRONGBRIDGE BIOPHARMA PLC, a public limited company incorporated under the laws of Ireland (the “Company”), that number of shares (the “Shares”) of the Company’s ordinary shares, of nominal value $0.01 per share (the “Ordinary Shares”), at such times and at the price per Share, set forth in Section 1. The term “Warrant” as used herein shall include this Warrant and any warrants delivered in substitution or exchange therefor as provided herein. This Warrant is issued in connection with the transactions described in the Term Loan Agreement, dated as of July 14, 2017, and amended as of January 16, 2018, by and between the Company, the Subsidiary Guarantors from time to time party thereto, the Lenders from time to time party thereto and CRG Servicing LLC.

LEASE
Office Reference • March 12th, 2018 • Strongbridge Biopharma PLC • Pharmaceutical preparations

For good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged and intending to be legally bound, by this Lease Landlord leases to Tenant and Tenant leases from Landlord the Premises in the Building as set forth and described on the Reference Page. The Reference Page, including all terms defined thereon, is incorporated as part of this Lease.

AMENDMENT 1 TO TERM LOAN AGREEMENT
Term Loan Agreement • March 12th, 2018 • Strongbridge Biopharma PLC • Pharmaceutical preparations • New York

THIS AMENDMENT 1 TO TERM LOAN AGREEMENT, dated as of January 16, 2018 (this “Amendment” and the date hereof, the “Amendment No. 1 Effective Date”) is made among STRONGBRIDGE U.S. INC., a Delaware corporation (“Lead Borrower”), STRONGBRIDGE BIOPHARMA PUBLIC LIMITED COMPANY, a public limited company incorporated under the laws of Ireland (“Parent”), CORTENDO CAYMAN LTD., an exempted company incorporated in the Cayman Islands (“Cayman Borrower”), STRONGBRIDGE IRELAND LIMITED, a private limited company incorporated under the laws of Ireland (“Irish Borrower”), CORTENDO AB (PUBL), a public limited liability company incorporated under the laws of Sweden with registration number 556537-6554 (“Swedish Borrower” and, together with the Lead Borrower, Parent, Cayman Borrower and Irish Borrower, each, a “Borrower” and collectively, “Borrowers”), CRG Servicing LLC, as administrative agent and collateral agent (in such capacity, “Administrative Agent”) and the lenders listed on the signature pages h

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