0001299933-08-001001 Sample Contracts

SECOND AMENDMENT TO RIGHTS AGREEMENT
Rights Agreement • February 25th, 2008 • Adventrx Pharmaceuticals Inc • Pharmaceutical preparations • New York

This Second Amendment to Rights Agreement (this “Amendment”) is entered into effective as of February 25, 2008 (the “Effective Date”) by and between Adventrx Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and Icahn Partners LP, Icahn Partners Master Fund LP and High River Limited Partnership (collectively, the “Icahn Purchasers”).

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