0001279569-16-003953 Sample Contracts

COMMON SHARES CARDIOME PHARMA CORP. UNDERWRITING AGREEMENT
Underwriting Agreement • July 26th, 2016 • Cardiome Pharma Corp • Pharmaceutical preparations • New York

Cardiome Pharma Corp., a corporation organized and existing under the laws of Canada (the “Company”), proposes to issue and sell, subject to the terms and conditions stated herein, to the several underwriters named in Schedule I hereto (the “Underwriters”) an aggregate of 10,000,000 common shares (the “Firm Shares”), without par value. In addition, for the sole purpose of covering over-allotments in connection with the sale of the Firm Shares, at the option of the Underwriters, the Company grants to the Underwriters the option to purchase up to an additional 1,500,000 common shares (the “Additional Shares” and, together with the Firm Shares, the “Shares”). Leerink Partners LLC (“Leerink”) is acting as the sole bookrunner and the representative of the Underwriters in connection with the offering and sale of the Shares contemplated herein (the “Offering”).

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