0001279569-14-001600 Sample Contracts

FIRST SUPPLEMENTAL WARRANT INDENTURE

Aptose Biosciences Inc., (Formerly LORUS THERAPEUTICS INC.) • October 7th, 2014 • Biological products, (no disgnostic substances)

• Company
  Aptose Biosciences Inc., (Formerly LORUS THERAPEUTICS INC.)
• Filed
  October 7th, 2014
• Industry
  Biological products, (no disgnostic substances)

BETWEEN: APTOSE BIOSCIENCES INC. (formerly Lorus Therapeutics Inc.), a company incorporated under the laws of Canada; (hereinafter called the “Company”);