0001279569-09-000595 Sample Contracts

Collaboration and License Agreement among Cardiome Pharma Corp., Merck Sharp & Dohme (Switzerland) GmbH and Merck & Co., Inc.
Collaboration and License Agreement • April 30th, 2009 • Cardiome Pharma Corp • Pharmaceutical preparations • New York

This Collaboration and License Agreement (this “Agreement”) is entered into as of April 8, 2009 (the “Execution Date”), by and among Cardiome Pharma Corp., a Canadian corporation with offices at 6190 Agronomy Rd., 6th Floor, Vancouver, B.C., Canada, V6T 1Z3 (“CARDIOME”), Merck Sharp & Dohme (Switzerland) GmbH, a company organized under the laws of Switzerland with offices at Rue de Lausanne 27, Sion, 1950, Switzerland (“MSD Switzerland”), and Merck & Co., Inc., a corporation organized under the laws of New Jersey with offices at One Merck Drive, Whitehouse Station, NJ 08889-0100, U.S.A. (“Merck & Co.” and, collectively with MSD Switzerland, “MERCK”). Each of MSD Switzerland, Merck & Co. and CARDIOME is sometimes referred to individually herein as a “Party” and collectively as the “Parties.”

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