DEPOSIT AGREEMENTDeposit Agreement • February 10th, 2023 • Citibank,N.A./ADR • Biological products, (no disgnostic substances) • New York
DEPOSIT AGREEMENT, dated as of November 2, 2018, by and among (i) Orchard Therapeutics plc, a public limited company incorporated under the laws of England and Wales, and its successors (the “Company”), (ii) CITIBANK, N.A., a national banking association organized under the laws of the United States of America (“Citibank”) acting in its capacity as depositary, and any successor depositary hereunder (Citibank in such capacity, the “Depositary”), and (iii) all Holders and Beneficial Owners of American Depositary Shares issued hereunder (all such capitalized terms as hereinafter defined).
ORCHARD THERAPEUTICS PLC and CITIBANK, N.A., as Depositary, and THE HOLDERS AND BENEFICIAL OWNERS OF AMERICAN DEPOSITARY SHARES OUTSTANDING UNDER THE TERMS OF THE DEPOSIT AGREEMENT, DATED AS OF November 2, 2018 Amendment No. 1 to the Deposit Agreement...Deposit Agreement • February 10th, 2023 • Citibank,N.A./ADR • Biological products, (no disgnostic substances) • New York
Exhibit (b) ORCHARD THERAPEUTICS PLCLetter Agreement • February 10th, 2023 • Citibank,N.A./ADR • Biological products, (no disgnostic substances)
Reference is hereby made to the Deposit Agreement, dated as of November 2, 2018, as amended and supplemented from time to time (the “Deposit Agreement”), by and among Orchard Therapeutics plc, a company organized under the laws of England and Wales (the “Company”), Citibank, N.A., a national banking association organized and existing under the laws of the United States of America, as Depositary (the “Depositary”), and all Holders and Beneficial Owners of American Depositary Shares (the “ADSs”) issued thereunder. All capitalized terms used, but not otherwise defined herein, shall have the meaning assigned thereto in the Deposit Agreement.
