0001193805-17-003229 Sample Contracts

Contract
JPMorgan Chase Bank, N.A. - ADR Depositary • October 4th, 2017 • American depositary receipts • New York

AMENDMENT NO. 1, dated as of , 2017 (the "Amendment"), to the Deposit Agreement dated as of September 5, 2014 (the "Deposit Agreement"), among Ablynx NV, incorporated under the laws of Belgium (the "Company"), JPMorgan Chase Bank, N.A., as depositary (the "Depositary"), and all holders from time to time of American depositary receipts ("ADRs") issued thereunder.

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