0001193125-26-398015 Sample Contracts

HALOZYME THERAPEUTICS, INC. and THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A. as Trustee INDENTURE Dated as of September 22, 2026 1.50% Convertible Senior Notes due 2033
Indenture • September 22nd, 2026 • Halozyme Therapeutics, Inc. • Biological products, (no disgnostic substances) • New York

INDENTURE, dated as of September 22, 2026, between Halozyme Therapeutics, Inc., a Delaware corporation, as issuer (the “Company”), and The Bank of New York Mellon Trust Company, N.A., not in its individual capacity but solely as trustee, registrar, paying agent and conversion agent (the “Trustee”).