0001193125-24-076669 Sample Contracts

DEVELOPMENT AND MANUFACTURING SERVICES AGREEMENT
Development and Manufacturing Services Agreement • March 26th, 2024 • AVROBIO, Inc. • Biological products, (no disgnostic substances) • New York

THIS DEVELOPMENT AND MANUFACTURING SERVICES AGREEMENT is made as of May 6, 2022(the Effective Date”)by and between Tectonic Therapeutic, Inc., a Delaware corporation with an office at 490 Arsenal Way, Suite 210, Watertown, MA 02472 U.S.A. (“Tectonic”) and WuXi Biologics (Hong Kong) Limited, a Hong Kong corporation with an office at Flat/RM826, 8/F Ocean Centre Harbour City, 5 Canton Road TST, Hong Kong (“Manufacturer”).

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LICENSE AGREEMENT
License Agreement • March 26th, 2024 • AVROBIO, Inc. • Biological products, (no disgnostic substances) • Massachusetts

This License Agreement (this “Agreement”) is entered into as of this 10th day of February, 2022 (the “Effective Date”), by and between Tectonic Therapeutic, Inc., a corporation existing under the laws of the State of Delaware, having a place of business at 490 Arsenal Way, Suite 210, Watertown, MA 02472 (“Licensee”) and President and Fellows of Harvard College, an educational and charitable corporation existing under the laws and the constitution of the Commonwealth of Massachusetts, having a place of business at Richard A. and Susan F. Smith Campus Center, Suite 727, 1350 Massachusetts Avenue, Cambridge, Massachusetts 02138 (“Harvard”).

MASTER CONTRACT SERVICES AGREEMENT
Master Contract Services Agreement • March 26th, 2024 • AVROBIO, Inc. • Biological products, (no disgnostic substances) • Massachusetts

THIS MASTER CONTRACT SERVICES AGREEMENT (together with Appendix A and any Statement(s) of Work (as defined in Section 1), the “Agreement”) is made on October 17, 2023 (the “Effective Date”) by and between Tectonic Therapeutic, Inc., a Delaware corporation with an office at 490 Arsenal Way, Suite 210, Watertown, MA 02472 USA (“Tectonic”) and QPS Holdings, LLC, a Delaware limited liability company, with an office at 3 Innovation Way, Delaware Technology Park, Newark, DE 19711 USA (“Service Provider”).

HAS BEEN OMITTED BECAUSE TECTONIC THERAPEUTIC, INC. HAS DETERMINED THE INFORMATION (I) IS NOT MATERIAL AND (II) IS THE TYPE THAT TECTONIC THERAPEUTIC, INC. TREATS AS PRIVATE OR CONFIDENTIAL.” MASTER CONTRACT SERVICES AGREEMENT
Master Contract Services Agreement • March 26th, 2024 • AVROBIO, Inc. • Biological products, (no disgnostic substances) • Massachusetts

THIS MASTER CONTRACT SERVICES AGREEMENT (together with Appendix A and any Statement(s) of Work (as defined in Section I), the “Agreement”) is made on February 16,2022 (the “Effective Date”) by and between Tectonic Therapeutic, Inc., a Delaware corporation with an office at 490 Arsenal Way, Suite 210, Watertown, MA 02472 (“Tectonic”) ITR LABORATORIES CANADA INC., a Canadian established corporation with an office at 19601 Clark Graham Avenue, Baie D’Urfe, Quebec H9X 3T1 Canada (“Service Provider”).

MASTER CLINICAL CONTRACT SERVICES AGREEMENT
Master Clinical Contract Services Agreement • March 26th, 2024 • AVROBIO, Inc. • Biological products, (no disgnostic substances) • England and Wales

THIS MASTER CLINICAL CONTRACT SERVICES AGREEMENT (together with Appendix A and any Statement(s) of Work (as defined in Section 1), the “Agreement”) is made on 06 March, 2023 (the “Effective Date”) by and between Tectonic Therapeutic, Inc., a Delaware corporation with an office at 490 Arsenal Way, Suite 210, Watertown, MA 02472 (“Tectonic”) and Novotech (Australia) Pty Limited ACN 071 874 881 an Australian proprietary limited company with an office at Level 3, 235 Pyrmont Street, Pyrmont, NSW 2009, Australia (“Service Provider” or “Novotech”).

Master Agreement for Early Phase Clinical Services
AVROBIO, Inc. • March 26th, 2024 • Biological products, (no disgnostic substances) • New York

Now, therefore, in consideration of the foregoing and the mutual covenants and promises contained in this Agreement and in any Work Order, the Parties hereto agree as follows:

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