0001193125-23-165273 Sample Contracts

IONIS PHARMACEUTICALS, INC. AND U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, as Trustee INDENTURE Dated as of June 12, 2023 1.75% Convertible Senior Notes due 2028
Indenture • June 12th, 2023 • Ionis Pharmaceuticals Inc • Pharmaceutical preparations • New York

INDENTURE dated as of June 12, 2023 between IONIS PHARMACEUTICALS, INC., a Delaware corporation, as issuer (the “Company,” as more fully set forth in Section 1.01) and U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, a national banking association, as trustee (the “Trustee,” as more fully set forth in Section 1.01).

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