0001193125-23-140832 Sample Contracts

AMENDMENT NO. 2 TO THE SALES AGREEMENT
The Sales Agreement • May 10th, 2023 • Beam Therapeutics Inc. • Biological products, (no disgnostic substances)

This Amendment No. 2 to the sales agreement (this “Amendment No. 2”) is entered into as of the date first written above by Beam Therapeutics Inc., a Delaware corporation (the “Company”), and Jefferies LLC (the “Agent”), that are parties to that certain sales agreement, dated April 1, 2021 (the “Original Agreement”), as amended by Amendment No. 1 to the Original Agreement, dated July 7, 2021 (“Amendment No. 1” and together with the Original Agreement, the “Sales Agreement”) relating to the offering of up to $800,000,000 of the Company’s Common Shares (as defined below).

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