0001193125-21-183167 Sample Contracts

Re: Executive Offer Letter
Graphite Bio, Inc. • June 4th, 2021 • Biological products, (no disgnostic substances) • California

Integral Medicines, Inc., a Delaware corporation (the “Company”), is pleased to offer you employment pursuant to the terms of this Executive Offer Letter (the “Agreement”).

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ADVISOR AGREEMENT
Advisor Agreement • June 4th, 2021 • Graphite Bio, Inc. • Biological products, (no disgnostic substances) • California

THIS ADVISOR AGREEMENT (this “Agreement”) is made and entered into as of 3/24/20 (the “Effective Date”), by and between INTEGRAL MEDICINES, INC., a Delaware corporation (the “Company”), and MATTHEW PORTEUS (“Advisor”). The Company and Advisor may be referred to herein individually as “Party” or collectively as “Parties”.

AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT
Investors’ Rights Agreement • June 4th, 2021 • Graphite Bio, Inc. • Biological products, (no disgnostic substances) • Delaware

THIS AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT (this “Agreement”), is made as of the 11th day of March, 2021, by and among Graphite Bio, Inc., a Delaware corporation (the “Company”), each of the investors listed on Schedule A hereto, each of which is referred to in this Agreement as an “Investor”, and each of the stockholders listed on Schedule B hereto, each of whom is referred to herein as a “Key Holder”.

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