0001193125-21-103389 Sample Contracts

STERIS IRISH FINCO UNLIMITED COMPANY as Issuer AND THE GUARANTORS PARTY HERETO AND U.S. BANK NATIONAL ASSOCIATION, as Trustee INDENTURE Dated as of April 1, 2021 DEBT SECURITIES
STERIS PLC • April 1st, 2021 • Orthopedic, prosthetic & surgical appliances & supplies • New York

THIS INDENTURE is dated as of April 1, 2021 among STERIS IRISH FINCO UNLIMITED COMPANY, a public unlimited company incorporated under the laws of Ireland (the “Company”), the Guarantors (as hereinafter defined) named herein and U.S. BANK NATIONAL ASSOCIATION, a national banking association, as trustee (the “Trustee”).

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STERIS IRISH FINCO UNLIMITED COMPANY AND THE GUARANTORS PARTY HERETO AND as Trustee FIRST SUPPLEMENTAL INDENTURE Dated as of April 1, 2021 $675,000,000 of 2.700% Senior Notes due 2031 $675,000,000 of 3.750% Senior Notes due 2051
First Supplemental Indenture • April 1st, 2021 • STERIS PLC • Orthopedic, prosthetic & surgical appliances & supplies • New York

THIS FIRST SUPPLEMENTAL INDENTURE (the “First Supplemental Indenture”) is dated as of April 1, 2021 among STERIS IRISH FINCO UNLIMITED COMPANY, a public unlimited company incorporated under the laws of Ireland (the “Company”), the Guarantors party hereto (the “Guarantors”) and U.S. BANK NATIONAL ASSOCIATION, a national banking association, as trustee (the “Trustee”).

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