0001193125-18-116023 Sample Contracts

WARRANT TO PURCHASE SHARES OF COMMON STOCK OF OMEROS CORPORATION Dated as of April 12, 2018 Void after the date specified in Section 8
Omeros Corp • April 13th, 2018 • Pharmaceutical preparations • Washington

THIS CERTIFIES THAT, for value received, CRG PARTNERS III – PARALLEL FUND “A” L.P., or its registered assigns (the “Holder”), is entitled, subject to the provisions and upon the terms and conditions set forth herein, to purchase from Omeros Corporation, a Washington corporation (the “Company”), shares of the Company’s common stock, par value $0.01 per share (such shares, the “Shares” and such common stock, the “Common Stock”), in the amounts, at such times and at the price per share set forth in Section 1. The term “Warrant” as used herein shall include this Warrant and any warrants delivered in substitution or exchange therefor as provided herein. This Warrant is issued in connection with the transactions described in Amendment No. 3 to Loan Agreement, dated as of April 10, 2018, by and among the Company, CRG Servicing LLC, as administrative and collateral agent, and the lenders party thereto, which amends that certain Term Loan Agreement, dated as of October 26, 2016 (as so amended a

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AMENDMENT NO. 3 TO LOAN AGREEMENT
Loan Agreement • April 13th, 2018 • Omeros Corp • Pharmaceutical preparations • New York

THIS AMENDMENT NO. 3 TO LOAN AGREEMENT, dated as of April 10, 2018 (this “Amendment”), is made among Omeros Corporation, a Washington corporation (“Borrower”), the Subsidiary Guarantors listed on the signature pages hereof, CRG Servicing LLC, as administrative agent and collateral agent (in such capacities, “Administrative Agent”), and the lenders listed on the signature pages hereof (each, a “Lender” and, collectively, the “Lenders”), with respect to the Loan Agreement referred to below.

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