0001193125-18-041486 Sample Contracts

SUCAMPO PHARMACEUTICALS, INC. AND as Trustee FIRST SUPPLEMENTAL INDENTURE Dated as of February 13, 2018
First Supplemental Indenture • February 13th, 2018 • Sucampo Pharmaceuticals, Inc. • Pharmaceutical preparations • New York

FIRST SUPPLEMENTAL INDENTURE, dated as of February 13, 2018 (this “Supplemental Indenture”), among Sucampo Pharmaceuticals, Inc., a Delaware corporation (the “Company”), as issuer, and U.S. Bank National Association, a national banking association organized under the laws of the United States of America, as trustee (the “Trustee”), to the Indenture, dated as of December 27, 2016 (as supplemented or otherwise modified prior to the date hereof, the “Indenture”), between the Company and the Trustee.

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