0001193125-17-344143 Sample Contracts

Contract
Miragen Therapeutics, Inc. • November 15th, 2017 • Services-medical laboratories • California

THIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR THE SECURITIES LAWS OF ANY STATE AND, EXCEPT AS SET FORTH IN SECTIONS 5.3 AND 5.4 BELOW, MAY NOT BE OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED UNLESS AND UNTIL REGISTERED UNDER SAID ACT AND LAWS OR, IN THE OPINION OF LEGAL COUNSEL IN FORM AND SUBSTANCE SATISFACTORY TO THE ISSUER, SUCH OFFER, SALE, PLEDGE OR OTHER TRANSFER IS EXEMPT FROM SUCH REGISTRATION.

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AMENDED AND RESTATED LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • November 15th, 2017 • Miragen Therapeutics, Inc. • Services-medical laboratories • Delaware

THIS AMENDED AND RESTATED LOAN AND SECURITY AGREEMENT (this “Agreement”) dated as of November 14, 2017 (the “Effective Date”), between SILICON VALLEY BANK, a California corporation (“Bank”), and MIRAGEN THERAPEUTICS, INC. a Delaware corporation (“Borrower”), provides the terms on which Bank shall lend to Borrower and Borrower shall repay Bank. This Agreement amends and restates in its entirety that certain Loan and Security Agreement, dated as of April 30, 2015, by and between Borrower and Miragen Therapeutics, Inc., a Delaware corporation and predecessor of Borrower, as amended by that certain First Loan Modification Agreement, dated as of December 22, 2016, and as further effected by that certain Assumption Agreement, by and between Borrower and Bank, dated as of February 13, 2017 (collectively, as in effect immediately prior to the date hereof, the “Prior Loan Agreement”). The parties agree as follows:

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