AMENDMENT NO. 1 TO CAPITAL ON DEMAND™ SALES AGREEMENTSales Agreement • August 21st, 2017 • ARCA Biopharma, Inc. • In vitro & in vivo diagnostic substances • New York
ARCA biopharma, Inc., a Delaware corporation (the “Company”), and JonesTrading Institutional Services LLC (the “Agent”), are parties to that certain Capital on Demand™ Sales Agreement dated January 11, 2017 (the “Original Agreement”). All capitalized terms not defined herein shall have the meanings ascribed to them in the Original Agreement. The parties, intending to be legally bound, hereby amend the Original Agreement pursuant to the terms of this amendment No. 1 to the Original Agreement (this “Amendment No. 1”) as follows (to be effective as set forth in paragraph 4 below):
