0001193125-17-080322 Sample Contracts

October 21, 2016 Eleanor L. Ramos, M.D. Re: Separation from Employment Dear Leni:
Global Blood Therapeutics, Inc. • March 13th, 2017 • Pharmaceutical preparations

This letter confirms our agreement concerning your departure from Global Blood Therapeutics, Inc. (the “Company”). Your last day of employment with the Company will be October 24, 2016 (the “Separation Date”).

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