0001193125-15-396804 Sample Contracts

KARYOPHARM THERAPEUTICS INC. Shares of Common Stock (par value $0.0001 per share) Controlled Equity OfferingSM Sales Agreement
Sales Agreement • December 8th, 2015 • Karyopharm Therapeutics Inc. • Pharmaceutical preparations • New York

Karyopharm Therapeutics Inc., a Delaware corporation (the “Company”), confirms its agreement (this “Agreement”) with Cantor Fitzgerald & Co. (the “Agent”), as follows:

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