0001193125-15-142499 Sample Contracts

— ] Shares Gelesis, Inc. Common Stock UNDERWRITING AGREEMENT
Underwriting Agreement • April 23rd, 2015 • Gelesis Inc • Pharmaceutical preparations • New York

Gelesis, Inc. (the “Company”) announced today that Piper Jaffray & Co. and Stifel, Nicolaus & Company, Incorporated, as the representatives of the underwriters, are [waiving] [releasing] [a] lock-up restriction[s] with respect to an aggregate of **[# of common shares] held by certain [officers] [directors] of the Company. These [officers] [directors] entered into lock-up agreements with the representatives in connection with the Company’s initial public offering.

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AMENDED AND RESTATED EMPLOYMENT AGREEMENT
Employment Agreement • April 23rd, 2015 • Gelesis Inc • Pharmaceutical preparations • Massachusetts

This Amended and Restated Employment Agreement (this “Agreement”) dated as of April 22, 2015, is by and between Gelesis, Inc., a Delaware corporation (“Employer”), and Robert Armstrong, Ph.D. (“Employee”).

FORM OF INDEMNIFICATION AGREEMENT
Form of Indemnification Agreement • April 23rd, 2015 • Gelesis Inc • Pharmaceutical preparations • Delaware

THIS INDEMNIFICATION AGREEMENT (the “Agreement”) is made and entered into as of , 2015, by and between Gelesis, Inc., a Delaware corporation (the “Corporation”), and (“Indemnitee”), with reference to the following facts:

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