0001193125-15-004114 Sample Contracts

LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • January 7th, 2015 • Auspex Pharmaceuticals, Inc. • Pharmaceutical preparations

THIS LOAN AND SECURITY AGREEMENT (as the same may from time to time be amended, modified, supplemented or restated, this “Agreement”) dated as of December 27, 2013 (the “Effective Date”) among OXFORD FINANCE LLC, a Delaware limited liability company with an office located at 133 North Fairfax Street, Alexandria, Virginia 22314 (“Oxford”), as collateral agent (in such capacity, “Collateral Agent”), the Lenders listed on Schedule 1.1 hereof or otherwise a party hereto from time to time including Oxford in its capacity as a Lender (each a “Lender” and collectively, the “Lenders”), and AUSPEX PHARMACEUTICALS, INC., a Delaware corporation with offices located at 3366 North Torrey Pines Court, Suite 225, La Jolla, California 92037 (“Borrower”), provides the terms on which the Lenders shall lend to Borrower and Borrower shall repay the Lenders. The parties agree as follows:

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FIFTH AMENDMENT TO LEASE
Work Letter Agreement • January 7th, 2015 • Auspex Pharmaceuticals, Inc. • Pharmaceutical preparations

THIS FIFTH AMENDMENT TO LEASE (“Fifth Amendment”) is made and entered into as of the 30th day of November, 2014, by and between MULLROCK 3 TORREY PINES, LLC, a Delaware limited liability company (“Landlord”) and AUSPEX PHARMACEUTICALS, INC., a Delaware corporation (“Tenant”).

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