0001193125-14-110621 Sample Contracts

AMENDMENT NO. 1 TO AT MARKET ISSUANCE SALES AGREEMENT
Market Issuance Sales Agreement • March 21st, 2014 • Galectin Therapeutics Inc • Pharmaceutical preparations • New York

Galectin Therapeutics, Inc., a Nevada corporation (the “Company”), and MLV & Co. LLC, a Delaware limited liability company (“MLV”), are parties to that certain At Market Issuance Sales Agreement dated October 25, 2013 (the “Original Agreement”). All capitalized terms not defined herein shall have the meanings ascribed to them in the Original Agreement. The parties, intending to be legally bound, hereby amend the Original Agreement as follows (to be effective as set forth in paragraph 4 below):

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