0001193125-13-336689 Sample Contracts

OPHTHOTECH CORPORATION Nonstatutory Stock Option Agreement Granted Under 2007 Stock Incentive Plan
Stock Option Agreement • August 15th, 2013 • Ophthotech Corp. • Pharmaceutical preparations
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Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. LICENSE, MANUFACTURING AND SUPPLY AGREEMENT
Agreement • August 15th, 2013 • Ophthotech Corp. • Pharmaceutical preparations • California

PRODUCT, and NEKTAR AL agrees to undertake the manufacture and supply of the REAGENT specified under this AGREEMENT in accordance with the terms and conditions specified under this AGREEMENT.

CONFIDENTIAL Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. July 27, 2007 DIVESTITURE AGREEMENT BETWEEN OPHTHOTECH CORPORATION AND (OSI) EYETECH, INC. EXECUTION VERSION
Divestiture Agreement • August 15th, 2013 • Ophthotech Corp. • Pharmaceutical preparations • New York

NOW, THEREFORE, in consideration of the foregoing premises and the mutual covenants herein contained, the Parties hereby agree as follows:

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. AMENDED AND RESTATED EXCLUSIVE LICENSE AGREEMENT
Exclusive License Agreement • August 15th, 2013 • Ophthotech Corp. • Pharmaceutical preparations • Massachusetts

This Amended and Restated Exclusive License Agreement (this “Agreement”) is made effective as of September 12, 2011 (the “Restatement Date”), by and between Archemix Corp, a Delaware corporation (“Archemix”), and Ophthotech Corporation, a Delaware corporation (“Ophthotech”). Archemix and Ophthotech are each hereinafter referred to individually as a “Party” and together as the “Parties.”

OPHTHOTECH CORPORATION Incentive Stock Option Agreement Granted Under 2007 Stock Incentive Plan
Incentive Stock Option Agreement • August 15th, 2013 • Ophthotech Corp. • Pharmaceutical preparations
SHORT FORM LEASE Between VAUGHN PRINCETON ASSOCIATES L.L.C. as Landlord, and OPHTHOTECH CORP. as Tenant Building: Princeton, New Jersey
Agreement • August 15th, 2013 • Ophthotech Corp. • Pharmaceutical preparations

THIS LEASE is made on the 8th day of Feb., 2010 between VAUGHN PRINCETON ASSOCIATES, L.L.C., a New Jersey limited liability company, whose address is c/o Mack-Cali Realty Corporation, 343 Thornall Street, Edison, New Jersey 08837-2206 (who is referred to in this Lease as “Landlord”) and OPHTHOTECH CORP., a , whose address is 5 Vaughn Drive, Princeton, New Jersey (who is referred to in this Lease as “Tenant”). This Lease consists of the following Basic Lease Provisions and Definitions and the attached General Conditions and Exhibits. The Basic Lease Provisions and Definitions are referred to in this Lease as the “Basic Lease Provisions.”

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