0001193125-13-111046 Sample Contracts

AMENDMENT
Apricus Biosciences, Inc. • March 18th, 2013 • Pharmaceutical preparations • New York

This AMENDMENT (“Amendment”) is made as of this 7th day of December, 2012 by and between Apricus Biosciences, Inc., formerly known as NexMed, Inc., a Nevada corporation (“Company”), and The Tail Wind Fund Ltd. (“Tail Wind”), Solomon Strategic Holdings, Inc. (“Solomon”) and Tail Wind Advisory & Management Ltd. (“TWAM”, and together with Tail Wind and Solomon, the “Holders”).

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REAL ESTATE PURCHASE AGREEMENT
Real Estate Purchase Agreement • March 18th, 2013 • Apricus Biosciences, Inc. • Pharmaceutical preparations • New Jersey

THIS REAL ESTATE PURCHASE AGREEMENT, made the 7th day of November, 2012 by and between NEXMED (U.S.A.) INC., a Delaware corporation, having an address at 11975 El Camino Real, Suite 300, San Diego, CA 92130 (hereinafter referred to as Seller”) and MAUJER, LLC, a New York limited liability company or its assigns as may be permitted below, having an address at 124-19 Metropolitan Avenue, Kew Gardens, New York 11415 (hereinafter referred to as “Purchaser”).

SEPARATION AGREEMENT AND MUTUAL RELEASE
Separation Agreement and Mutual Release • March 18th, 2013 • Apricus Biosciences, Inc. • Pharmaceutical preparations • California

This Separation Agreement and Mutual Release (the “Agreement”) is entered into as of December 28, 2012 (the “Effective Date”) by and between Bassam Damaj (“Damaj”) and Apricus Biosciences, Inc. and its affiliates and subsidiaries (collectively, the “Company”). Damaj and the Company are the “Parties”.

AGREEMENT
Agreement • March 18th, 2013 • Apricus Biosciences, Inc. • Pharmaceutical preparations • New Jersey

AGREEMENT, made the 28th day of December, 2012 by and between NEXMED (USA) INC., a Delaware corporation, having an address at 11975 El Camino Real, Suite 300, San Diego, CA 92130 (hereinafter referred to as Seller”) and JACK BREITKOPF, or an assignee as permitted in paragraph 23 below, having an address at 69-21 Fleet Street, Forest Hills, New York 11375 (hereinafter referred to as “Purchaser”).

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