0001193125-12-257433 Sample Contracts

SUBSIDIARY GUARANTY
Subsidiary Guaranty • June 4th, 2012 • Express Scripts Holding Co. • Retail-drug stores and proprietary stores • New York

This SUBSIDIARY GUARANTY is entered into as of April 2, 2012, by and among THE UNDERSIGNED (each a “Guarantor”, and, together with any Additional Guarantors (as hereinafter defined), collectively the “Guarantors”) in favor of and for the benefit of Credit Suisse AG, Cayman Islands Branch, as agent for and representative of (in such capacity herein called “Guarantied Party”) the financial institutions party to the Credit Agreement (as hereinafter defined) (the “Lenders”) referred to below, and, subject to subsection 3.12, for the benefit of the other Beneficiaries (as hereinafter defined).

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SECOND SUPPLEMENTAL INDENTURE
Second Supplemental Indenture • June 4th, 2012 • Express Scripts Holding Co. • Retail-drug stores and proprietary stores • New York

The Supplemental Indenture (this “Second Supplemental Indenture”), dated as of May 29, 2012, among Medco Health Solutions, Inc., a corporation duly organized and existing under the laws of the State of Delaware (the “Company”), the Guarantors listed as signatories hereto (each, an “Existing Guarantor” and collectively, the “Existing Guarantors”) and certain subsidiaries of the Company, listed as signatories hereto (each, an “Additional Guarantor,” and, collectively, the “Additional Guarantors” and, together with the Existing Guarantors, the Guarantors”) and U.S. Bank Trust National Association, as trustee under the indenture referred to below (the “Trustee”).

NINTH SUPPLEMENTAL INDENTURE
Ninth Supplemental Indenture • June 4th, 2012 • Express Scripts Holding Co. • Retail-drug stores and proprietary stores • New York

The Ninth Supplemental Indenture (this “Ninth Supplemental Indenture”), dated as of May 29, 2012, among Express Scripts Holding Company (formerly Aristotle Holding, Inc.), a corporation duly organized and existing under the laws of the State of Delaware (the “Company”), the Guarantors listed as signatories hereto (each, an “Existing Guarantor” and collectively, the “Existing Guarantors”) and certain subsidiaries of Medco Health Solutions, Inc., a Delaware corporation, listed as signatories hereto (each, an “Additional Guarantor,” and, collectively, the “Additional Guarantors”) and Wells Fargo Bank, National Association, as trustee under the indenture referred to below (the “Trustee”).

NINTH SUPPLEMENTAL INDENTURE
Ninth Supplemental Indenture • June 4th, 2012 • Express Scripts Holding Co. • Retail-drug stores and proprietary stores • New York

The Ninth Supplemental Indenture (this “Ninth Supplemental Indenture”), dated as of May 29, 2012, among Express Scripts, Inc., a corporation duly organized and existing under the laws of the State of Delaware (the “Company”), the Guarantors listed as signatories hereto (each, an “Existing Guarantor” and collectively, the “Existing Guarantors”) and certain subsidiaries of Medco Health Solutions, Inc., a Delaware corporation, listed as signatories hereto (each, an “Additional Guarantor,” and, collectively, the “Additional Guarantors”) and Union Bank, N.A., a national association, as trustee under the indenture referred to below (the “Trustee”).

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