0001193125-11-321131 Sample Contracts

PUMA BIOTECHNOLOGY, INC. SUBSCRIPTION AGREEMENT
Registration Rights Agreement • November 23rd, 2011 • Puma Biotechnology, Inc. • Pharmaceutical preparations • New York

The undersigned investor (the “Investor”) hereby confirms its agreement with Puma Biotechnology, Inc., a Delaware corporation (the “Company”), as follows:

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AMENDMENT NO. 1 TO REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • November 23rd, 2011 • Puma Biotechnology, Inc. • Pharmaceutical preparations • New York

This Amendment No. 1 (this “Amendment”) to that certain Registration Rights Agreement, dated as of October 4, 2011 (the “Registration Rights Agreement”), by and among Puma Biotechnology, Inc., a Delaware corporation (the “Corporation”), Innovative Acquisitions Corp., a Delaware corporation (“IAC”), and the persons listed on Exhibit A attached thereto (the “Investors”), is made and entered into as of November 18, 2011. Capitalized terms used herein and not otherwise defined shall have the meanings ascribed to them in the Registration Rights Agreement.

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