0001193125-11-006874 Sample Contracts

•] Shares Pacira Pharmaceuticals, Inc. Common Stock UNDERWRITING AGREEMENT
Underwriting Agreement • January 13th, 2011 • Pacira Pharmaceuticals, Inc. • Pharmaceutical preparations • New York

Pacira Pharmaceuticals, Inc., a Delaware corporation (the “Company”), proposes to sell [•] shares (the “Firm Stock”) of the Company’s common stock, par value $0.001 per share (the “Common Stock”). In addition, the Company proposes to grant to the underwriters (the “Underwriters”) named in Schedule I attached to this agreement (this “Agreement”) an option to purchase up to [•] additional shares of the Common Stock on the terms set forth in Section 2 (the “Option Stock”). The Firm Stock and the Option Stock, if purchased, are hereinafter collectively called the “Stock”. This Agreement is to confirm the agreement concerning the purchase of the Stock from the Company by the Underwriters.

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PACIRA PHARMACEUTICALS, INC. INDEMNIFICATION AGREEMENT
Indemnification Agreement • January 13th, 2011 • Pacira Pharmaceuticals, Inc. • Pharmaceutical preparations • Delaware

This Indemnification Agreement made and entered into this day of , (the “Agreement”), by and between Pacira Pharmaceuticals, Inc., a Delaware corporation (the “Company,” which term shall include, where appropriate, any Entity (as hereinafter defined) controlled directly or indirectly by the Company) and (the “Indemnitee”):

DATED: OCTOBER 15, 2009 PACIRA PHARMACEUTICALS, INC. and EKR THERAPEUTICS, INC. AMENDED AND RESTATED STRATEGIC LICENSING, DISTRIBUTION AND MARKETING AGREEMENT
Distribution and Marketing Agreement • January 13th, 2011 • Pacira Pharmaceuticals, Inc. • Pharmaceutical preparations • New York

THIS AMENDED AND RESTATED STRATEGIC LICENSING, DISTRIBUTION AND MARKETING AGREEMENT (the “Agreement”) is made on October 15, 2009 (the “Agreement Date”) and is effective as of the Effective Date (as defined below), between:

AMENDED AND RESTATED SUPPLY AGREEMENT
Supply Agreement • January 13th, 2011 • Pacira Pharmaceuticals, Inc. • Pharmaceutical preparations • New York

THIS AMENDED AND RESTATED SUPPLY AGREEMENT is entered into on October 15, 2009 (the “Agreement Date”) and is made effective as of the 10th day of August, 2007 (the “Effective Date”)

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Distribution Agreement • January 13th, 2011 • Pacira Pharmaceuticals, Inc. • Pharmaceutical preparations

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions.

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Distribution Agreement • January 13th, 2011 • Pacira Pharmaceuticals, Inc. • Pharmaceutical preparations

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions.

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Supply Agreement • January 13th, 2011 • Pacira Pharmaceuticals, Inc. • Pharmaceutical preparations

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions.

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Strategic Marketing Agreement • January 13th, 2011 • Pacira Pharmaceuticals, Inc. • Pharmaceutical preparations

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions.

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