0001193125-10-140217 Sample Contracts

Number of Shares] TRIUS THERAPEUTICS, INC. Common Stock, par value $0.0001 per share UNDERWRITING AGREEMENT
Underwriting Agreement • June 16th, 2010 • Trius Therapeutics Inc • Pharmaceutical preparations • New York
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RESEARCH AGREEMENT HDTRA1-10-C-0004
Research Agreement • June 16th, 2010 • Trius Therapeutics Inc • Pharmaceutical preparations

THIS RESEARCH AGREEMENT (“Agreement”) is made by and between TRIUS THERAPEUTICS, INC. (“Sponsor”) with offices at 6310 Nancy Ridge Drive, Suite 101, San Diego, CA 92121, and THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, a California Corporation having its principal office at 1111 Franklin Street, 5th floor, Oakland, California 94607-5200, on behalf of Scripps Institution of Oceanography at the University of California, San Diego campus (“University”) located at 9500 Gilman Drive, La Jolla, California 92093-0210.

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