0001193125-07-067406 Sample Contracts

WYETH $500,000,000 5.450% Notes Due 2017 $2,000,000,000 5.950% Notes Due 2037 UNDERWRITING AGREEMENT March 22, 2007
Underwriting Agreement • March 28th, 2007 • Wyeth • Pharmaceutical preparations • New York

Wyeth, a Delaware corporation (the “Company”), proposes to issue and sell to the several Underwriters listed in Schedule 1 hereto (the “Underwriters”) $500,000,000 aggregate principal amount of its 5.450% Notes Due 2017 (the “2017 Notes”) and $2,000,000,000 aggregate principal amount of its 5.950% Notes Due 2037 (the “2037 Notes”, together with the 2017 Notes, the “Notes”) . The Notes will be issued as separate series of debt securities under a supplemental indenture (the “Supplemental Indenture”) to be dated as of March 27, 2007 between the Company and The Bank of New York, as successor trustee (the “Trustee”). The Supplemental Indenture relates to an indenture dated as of April 10, 1992, as amended on October 13, 1992, between the Company and the Trustee (the “Base Indenture”, and as further amended and supplemented by the Supplemental Indenture, the “Indenture”).

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Contract
Seventh Supplemental Indenture • March 28th, 2007 • Wyeth • Pharmaceutical preparations • New York

SEVENTH SUPPLEMENTAL INDENTURE, dated as of March 27, 2007 (this “Seventh Supplemental Indenture”), between WYETH, a Delaware corporation (formerly known as American Home Products Corporation) (the “Issuer”) and THE BANK OF NEW YORK (as successor to JPMORGAN CHASE BANK), a banking corporation duly organized and existing under the laws of the State of New York, as trustee (the “Trustee”).

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