0001193125-06-230088 Sample Contracts

SECURITY AGREEMENT
Security Agreement • November 9th, 2006 • Nanogen Inc • Laboratory analytical instruments • New York

THIS SECURITY AGREEMENT is made as of the 29th day of September, 2006 between Drug Royalty Trust 9, a Delaware trust acting through its manager (“Secured Party”), located in care of Drug Royalty Corporation Inc. in its capacity as manager, at Royal Bank Plaza, Suite 3120, South Tower, Box 122, 200 Bay Street, Toronto, ON M5J 2J3, Canada, and Epoch Biosciences, Inc., a corporation organized and existing under the laws of the State of Delaware (“Debtor”), with its principal executive offices at 10398 Pacific Center Court, San Diego, CA 92121.

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AMENDED AND RESTATED INDEPENDENT CONTRACTOR AGREEMENT FOR CONSULTING SERVICES
Independent Contractor Agreement • November 9th, 2006 • Nanogen Inc • Laboratory analytical instruments • California

This Independent Contractor Agreement for Consulting Services (the “Agreement”), dated November 6, 2006 is entered into by and between NANOGEN, INC., a Delaware corporation (the “Company”) with its principal place of business at 10398 Pacific Center Court, San Diego, CA 92121 and HEINER DREISMANN (“Consultant”).

ROYALTY INTEREST ASSIGNMENT AGREEMENT between EPOCH BIOSCIENCES, INC. as Assignor and DRUG ROYALTY TRUST 9 as Assignee and NANOGEN, INC. as Guarantor September 29, 2006
Royalty Interest Assignment Agreement • November 9th, 2006 • Nanogen Inc • Laboratory analytical instruments • New York

WHEREAS Assignor is a party to a Second Amended and Restated Collaboration, License and Supply agreement with Applera Corporation (the “Licensee”) dated as of August 17, 2000, as amended by the First Side Agreement dated October 31, 2001, the Amendment No. 1 to the Second Amended and Restated Collaboration, License and Supply Agreement dated July 26, 2002 and Amendment No. 2 to the Second Amended and Restated Collaboration, License and Supply Agreement dated as of December 31, 2005 (as amended, the “License Agreement”);

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