0001193125-06-170360 Sample Contracts

NORTH CAROLINA ) ) SECOND LEASE AMENDMENT FORSYTH COUNTY )
Forsyth County • August 11th, 2006 • Targacept Inc • Pharmaceutical preparations

This Second Lease Amendment (“Amendment”), made effective as of the 31st day of March, 2006 (the “Amendment Date”), by and between Wake Forest University Health Sciences, a North Carolina non-profit corporation having its principal office in Winston-Salem, North Carolina (“Landlord”); and Targacept, Inc., a Delaware corporation having its principal office in Winston-Salem, North Carolina (“Tenant”), amends that Lease entered into between the parties effective August 1, 2002 as amended by First Lease Amendment effective January 1, 2005 (the “Lease”).

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