0001193125-06-120226 Sample Contracts

AMENDED AND RESTATED JOINT PATENT OWNERSHIP AND LICENSE AGREEMENT May 23, 2006
Joint Patent Ownership and License Agreement • May 26th, 2006 • CardioVascular BioTherapeutics, Inc. • Pharmaceutical preparations • California

This Joint Patent Ownership and License Agreement (the “Agreement”) entered into as of the 16th day of August 2004 (the “Effective Date”) between CardioVascular BioTherapeutics, Inc. (“CARDIO”), whose principal place of business is at 1635 Village Center Circle, Suite 250, Las Vegas, NV 89134, and Phage Biotechnology Corporation (“PHAGE”), whose principal place of business is at 1635 Village Center Circle, Suite 240, Las Vegas, NV 89134 and as amended on March 16, 2006 by letter agreement between the parties and further amended and restated as of the date first set forth above, to be effective as of the Effective Date.

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AMENDMENT NO. 1 TO CONTROLLING STOCKHOLDERS AGREEMENT
Controlling Stockholders Agreement • May 26th, 2006 • CardioVascular BioTherapeutics, Inc. • Pharmaceutical preparations

This Amendment No. 1 to Controlling Stockholders Agreement (“First Amendment”) is dated as of April 13, 2006, by and among each of the holders of common stock (“common stock”) of CardioVascular BioTherapeutics, Inc., a Delaware corporation (“Cardio”), listed below as signatories hereof (each a “Stockholder” and collectively, the “Stockholders”).

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