0001193125-06-053759 Sample Contracts

AMENDMENT NO. 1 TO AAD DEVICE SUPPLY AGREEMENT December 2, 2005 (effective October 1, 2005)
Aad Device Supply Agreement • March 14th, 2006 • Cotherix Inc • Biological products, (no disgnostic substances) • Delaware

This Amendment No. 1 to AAD Device Supply Agreement (“Amendment”) is made this second day of December, 2005, effective as of October 1, 2005, by and between Respironics Respiratory Drug Delivery (UK) Ltd., formerly known as Profile Drug Delivery Ltd., with its principal place of business at Heath Place, Bognor Regis, West Sussex, PO22 9SL, United Kingdom (“Respironics RDD UK”), and CoTherix, Inc. with its principal place of business at 5000 Shoreline Court, Suite 101, South San Francisco, California 94080 (“CoTherix”).

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COTHERIX LETTERHEAD]
Cotherix Inc • March 14th, 2006 • Biological products, (no disgnostic substances)
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