0001193125-05-120785 Sample Contracts

AMENDMENT NO. 1 TO DEVELOPMENT, LICENSE AND SUPPLY AGREEMENT Dated as of May 24, 2005 among ETHYPHARM, S.A. 92213 Saint Cloud France and RELIANT PHARMACEUTICALS, INC. Liberty Corner, New Jersey 07938 United States
License and Supply Agreement • June 6th, 2005 • Reliant Pharmaceuticals, Inc. • Pharmaceutical preparations • New Jersey

AMENDMENT NO. 1 TO DEVELOPMENT, LICENSE AND SUPPLY AGREEMENT (this “Amendment”) is hereby entered into as of May 24, 2005, by and among ETHYPHARM S.A., a corporation organized under the laws of France, with its principal offices at 194 Bureaux de la Colline, 92213 Saint Cloud, France (“ETHYPHARM”), and RELIANT PHARMACEUTICALS, INC., a corporation organized under the laws of the State of Delaware, with its principal offices at 110 Allen Road, Liberty Corner, New Jersey 07938, United States of America, and successor by conversion to Reliant Pharmaceuticals, LLC (“RELIANT”).

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CONSENT, WAIVER AND AMENDMENT TO THIRD-LIEN LOAN AND GUARANTY AGREEMENT
Loan and Guaranty Agreement • June 6th, 2005 • Reliant Pharmaceuticals, Inc. • Pharmaceutical preparations

This CONSENT AND AMENDMENT, dated as of May 24, 2005 (this “Amendment”), to the Third-Lien Loan & Guaranty Agreement, dated as of April 13, 2005 (the “Agreement”) by and among RELIANT PHARMACEUTICALS, INC., a corporation organized under the laws of the state of Delaware (“Company”), CERTAIN SUBSIDIARIES OF COMPANY, as Guarantor Subsidiaries, the Lenders party thereto from time to time, and GOLDMAN SACHS CREDIT PARTNERS L.P. (“GSCP”) as Administrative Agent and Collateral Agent, is by and among the Company, GSCP, the Requisite Lenders signatory hereto and FIRST SOURCE FINANCIAL, INC. as successor administrative agent and successor collateral agent (“First Source”). Capitalized terms used and not defined herein shall have the meanings ascribed thereto in the Agreement.

AMENDED AND RESTATED PROMOTION AGREEMENT BETWEEN NOVARTIS PHARMACEUTICALS CORPORATION AND RELIANT PHARMACEUTICALS, INC.
Promotion Agreement • June 6th, 2005 • Reliant Pharmaceuticals, Inc. • Pharmaceutical preparations • New Jersey

This AMENDED AND RESTATED PROMOTION AGREEMENT, dated and effective the 5th day of April, 2005 (this “Agreement”), is made by and between Novartis Pharmaceuticals Corporation, a Delaware corporation, having offices at 59 Route 10, East Hanover, New Jersey 07936 (hereinafter “Novartis”) and Reliant Pharmaceuticals, Inc., a Delaware corporation (f/k/a Reliant Pharmaceuticals, LLC), having offices at 110 Allen Road, Liberty Corner, New Jersey 07938 (hereinafter “Reliant”).

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