0001193125-05-049565 Sample Contracts

TO ZymoGenetics’s Form 10-K For the Year Ended December 31, 2004
Zymogenetics Inc • March 14th, 2005 • Biological products, (no disgnostic substances) • New York

This Agreement, effective as of October 4, 2004 (the “Effective Date”), is entered into by and among ZymoGenetics, Inc., a Washington corporation whose address is 1201 Eastlake Ave. East, Seattle, WA 98102 (“ZGEN”), Novo Nordisk A/S, a Danish corporation whose address is Novo Allé, DK-2880, Bagsvaerd, Denmark (“Novo”), and Novo Nordisk Health Care AG, a Swiss corporation and wholly-owned affiliate of Novo whose address is Andreasstrasse 15, 8050 Zürich, Switzerland (“NN”). ZGEN and NN are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

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STRATEGIC ALLIANCE AGREEMENT by and between ZymoGenetics, Inc. and Serono S.A. Effective Date: October 12, 2004
Strategic Alliance Agreement • March 14th, 2005 • Zymogenetics Inc • Biological products, (no disgnostic substances) • New York

This Strategic Alliance Agreement is made as of the Effective Date, October 12, 2004, by and between ZymoGenetics, Inc., a Washington corporation (“ZGEN”), and Serono S.A., a Swiss corporation (“Serono”).

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