0001193125-04-135886 Sample Contracts

BIOMARIN PHARMACEUTICAL INC. LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • August 9th, 2004 • Biomarin Pharmaceutical Inc • Pharmaceutical preparations • California

This LOAN AND SECURITY AGREEMENT is entered into as of May 14, 2004, by and between COMERICA BANK (“Bank”) and BIOMARIN PHARMACEUTICAL INC. (“Borrower”).

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THIRD AMENDMENT TO LEASE
To Lease • August 9th, 2004 • Biomarin Pharmaceutical Inc • Pharmaceutical preparations

This Third Amendment to the Lease (“Third Amendment”) is made effective as of May 27, 2004, by and between Digital Drive, LLC, as to an undivided 83.6634% interest, Eastman Family LLC, as to an undivided 3,1296% interest, Basalacchi Family LLC as to an undivided 2.5037% interest, and Atkinson Family LLC as to an undivided 10.7033% interest, as successors in interest to Raymond Nizibian and Mildred Louise Nizibian, Trustees of the Raymond and Mildred Louise Nizibian Trust dated April 23,1992, as to an undivided 50% interest and Raymond V. Eastman and Barbara R. Eastman, Co-Trustees for the Raymond V. Eastman and Barbara R. Eastman Family Trust UDT, dated December 4,1991 as to an undivided 50% interest, as tenants in common, (as successor in interest to G.W. REALTY PARTNERS) (“Landlord”), and BioMarin Pharmaceutical Inc., a Delaware corporation (“Tenant”) who agree as follows:

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